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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Thymoquinone, Propranolol
Phytochemical Name Thymoquinone (PubChem CID: 10281 )
Anticancer drug Name Propranolol (PubChem CID: 4946 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 754
Pair Name Thymoquinone, Propranolol
Disease Info [ICD-11: 2C23.Z] Laryngeal cancer Investigative
Biological Phenomena Induction-->Apoptosis
Gene Regulation Up-regulation Expression BAX hsa581
Down-regulation Expression BCL2 hsa596
Up-regulation Expression CASP3 hsa836
Down-regulation Expression CCND1 hsa595
Up-regulation Expression TP53 hsa7157
Up-regulation Expression VEGFA hsa7422
In Vitro Model Hep-G2 Hepatoblastoma Homo sapiens (Human) CVCL_0027
Result The effect of thymoquinone and propranolol combination on epidermoid laryngeal carcinoma cell.
03. Reference
No. Title Href
1 The effect of thymoquinone and propranolol combination on epidermoid laryngeal carcinoma cell. Eur Arch Otorhinolaryngol. 2023 Jun;280(6):2849-2858. doi: 10.1007/s00405-023-07825-0. Click
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